Crossword clues for the word: WRYEST The word WRYEST has appeared as an answer to at least 11 crossword clues on different crossword puzzles. Crossword clues for WRYEST Showing 1 to 11 of 11 results Clue(s) "Most sardonic, as humor" Most bitterly amusing Most darkly droll Most full of ironic humor Most ironic Most ironically amusing Most ironically funny Most perverse Most sardonic Superlatively ironic Superlatively perverse