Crossword clues for the word: UPSANDDOWNS The word UPSANDDOWNS has appeared as an answer to at least 9 crossword clues on different crossword puzzles. Crossword clues for UPSANDDOWNS Showing 1 to 9 of 9 results Clue(s) "Judge: ""You've had some --"" Defendant: ""___""" "Vicissitudes of life, as for the inventor named in the circled squares?" Business trends Fickleness of life Good and bad days a lift operator knows all about Good times and bad Twists of fate Twists of fortune Vicissitudes