Crossword clues for the word: TWOSIX The word TWOSIX has appeared as an answer to at least 2 crossword clues on different crossword puzzles. Crossword clues for TWOSIX Showing 1 to 2 of 2 results Clue(s) "Slang term for the Canadian equivalent of a 750 mL bottle of liquor, based on the number of ounces in it (which makes no sense because we use metric here but I never like to argue with drunks)" Start of a nautical heave chant