Crossword clues for the word: TWERPS The word TWERPS has appeared as an answer to at least 9 crossword clues on different crossword puzzles. Crossword clues for TWERPS Showing 1 to 9 of 9 results Clue(s) Annoying little jerks Annoying sorts Insignificant fellows Insignificant ones Little rugrats Pipsqueaks Puny people Silly ones: Slang. Weenies