Crossword clues for the word: TIREOUT The word TIREOUT has appeared as an answer to at least 6 crossword clues on different crossword puzzles. Crossword clues for TIREOUT Showing 1 to 6 of 6 results Clue(s) "Exhaust, or the result of a flat?" Exhaust Get exhausted (2 wds.) Lose vim and vigor Make fatigued Wear down with fatigue