Crossword clues for the word: STANDUPTO The word STANDUPTO has appeared as an answer to at least 6 crossword clues on different crossword puzzles. Crossword clues for STANDUPTO Showing 1 to 6 of 6 results Clue(s) Confront fearlessly. Confront or resist courageously Defend oneself before Face down Face with cojones Refuse to back down.