Crossword clues for the word: SOULSISTER The word SOULSISTER has appeared as an answer to at least 6 crossword clues on different crossword puzzles. Crossword clues for SOULSISTER Showing 1 to 6 of 6 results Clue(s) "African-American woman, in 1970's slang: 2 wds." Best black female friend Girl's best friend? Rare groove DJ with an apt name Woman's best female friend Woman's kindred spirit