Crossword clues for the word: SMALLPOX The word SMALLPOX has appeared as an answer to at least 6 crossword clues on different crossword puzzles. Crossword clues for SMALLPOX Showing 1 to 6 of 6 results Clue(s) Contagious disease Eradicated disease Health scourge now deemed eradicated Its last U.S. case was in 1949 Plow puller Short goes viral and is contagious?