Crossword clues for the word: SETLOOSE The word SETLOOSE has appeared as an answer to at least 8 crossword clues on different crossword puzzles. Crossword clues for SETLOOSE Showing 1 to 8 of 8 results Clue(s) "Release, as the hounds" Free from bondage Let free Make free Release Release (2 wds.) Unleash Unleashed