Crossword clues for the word: SAMANTHAWHO The word SAMANTHAWHO has appeared as an answer to at least 2 crossword clues on different crossword puzzles. Crossword clues for SAMANTHAWHO Showing 1 to 2 of 2 results Clue(s) 2007-2009 ABC series where Jean Smart played Regina, the mother of an amnesiac daughter: 2 wds. 2007-2009 ABC sitcom starring Christina Applegate as a recovering amnesiac: 2 wds.