Crossword clues for the word: ROUTESIXTYSIX The word ROUTESIXTYSIX has appeared as an answer to at least 2 crossword clues on different crossword puzzles. Crossword clues for ROUTESIXTYSIX Showing 1 to 2 of 2 results Clue(s) Highway originally from Chicago to Santa Monica Theme of this puzzle, which winds its way nearly 2,500 miles through all the shaded squares herein