Crossword clues for the word: PIO The word PIO has appeared as an answer to at least 9 crossword clues on different crossword puzzles. Crossword clues for PIO Showing 1 to 9 of 9 results Clue(s) "Devout, in Spain" "Devout, to da Vinci" "Religious, in Roma" Devout: Span. Early Californian Pico Godly: It. Piety: It. Religious: It. Spanish author Baroja y Nessi