Crossword clues for the word: OPERATE The word OPERATE has appeared as an answer to at least 60 crossword clues on different crossword puzzles. Crossword clues for OPERATE Showing 51 to 60 of 60 results Clue(s) Urn Use a scalpel, say Use the OR Wield a scalpel Work Work and work with energy on speed Work on an open-and-shut case? Work or run Work with old and extremely polite judge Work, or do a surgeon's work « Previous Next » 1 2