Crossword clues for the word: NEUSE The word NEUSE has appeared as an answer to at least 7 crossword clues on different crossword puzzles. Crossword clues for NEUSE Showing 1 to 7 of 7 results Clue(s) N. C. river. N.C. river North Carolina waterway River in N.C. River into Pamlico Bay. River of North Carolina River to Pamlico Bay.