Crossword clues for the word: MOTHERLODE The word MOTHERLODE has appeared as an answer to at least 11 crossword clues on different crossword puzzles. Crossword clues for MOTHERLODE Showing 1 to 11 of 11 results Clue(s) *Bonanza "In the ___, there's the greatest concentration of ___" 1982 adventure flick directed by and starring Charlton Heston Gold miner's bonanza Gold seeker's target Major supply Miner's dream Prime ore source Prospector's dream Rich source of anything Sierra Nevada find.