Crossword clues for the word: MEPHISTOPHELEAN The word MEPHISTOPHELEAN has appeared as an answer to at least 2 crossword clues on different crossword puzzles. Crossword clues for MEPHISTOPHELEAN Showing 1 to 2 of 2 results Clue(s) Devilish; crafty Setter, this setter, to pause - he needs rest following Beelzebub