Crossword clues for the word: MELPOMENE The word MELPOMENE has appeared as an answer to at least 5 crossword clues on different crossword puzzles. Crossword clues for MELPOMENE Showing 1 to 5 of 5 results Clue(s) Connoisseur of tragedy Muse of tragedy Muse of tragedy in Greek mythology Tragedian's inspiration Tragedy Muse