Crossword clues for the word: LOSEHOPE The word LOSEHOPE has appeared as an answer to at least 7 crossword clues on different crossword puzzles. Crossword clues for LOSEHOPE Showing 1 to 7 of 7 results Clue(s) Become despondent Desperate thing to do Give up Give up all expectations Grow pessimistic Stop looking for a rescue plane To run out a twisted hose is a desperate thing to do!