Crossword clues for the word: ISTHATSO The word ISTHATSO has appeared as an answer to at least 11 crossword clues on different crossword puzzles. Crossword clues for ISTHATSO Showing 1 to 11 of 11 results Clue(s) “Really?” 'Oh really?' """Oh really now?""" "No kidding!" "Oh, really?" (3 wds.) Really - it's confusing for Panama plant reportedly! Response to a remarkable remark Response to a surprising statement Skeptic's query Skeptical question: 3 wds. Wryly incredulous query