Crossword clues for the word: IRRITATION The word IRRITATION has appeared as an answer to at least 4 crossword clues on different crossword puzzles. Crossword clues for IRRITATION Showing 1 to 4 of 4 results Clue(s) Painfulness The pea, in "The Princess and the Pea" Watering cans good for surface tension, which is a nuisance Watering requires tons, not gallons – that's a bother