Crossword clues for the word: IRRESPONSIBLE The word IRRESPONSIBLE has appeared as an answer to at least 4 crossword clues on different crossword puzzles. Crossword clues for IRRESPONSIBLE Showing 1 to 4 of 4 results Clue(s) *Van Heusen/Cahn classic Harebrained and unreliable Reckless and unreliable (behaviour) Unreliable