Crossword clues for the word: HOUSTONASTROS The word HOUSTONASTROS has appeared as an answer to at least 3 crossword clues on different crossword puzzles. Crossword clues for HOUSTONASTROS Showing 1 to 3 of 3 results Clue(s) AL West team that lost 111 games in 2013, then won the World Series four years later: 2 wds. Team whose first game was in 1965 They won their first World Series in 2017