Crossword clues for the word: ENDORPHIN The word ENDORPHIN has appeared as an answer to at least 3 crossword clues on different crossword puzzles. Crossword clues for ENDORPHIN Showing 1 to 3 of 3 results Clue(s) Heroin in Pernod, when mixed, makes a natural painkiller It causes a runner's high Target or point in receiving injection of hard brain chemical