Crossword clues for the word: DESPONDENT The word DESPONDENT has appeared as an answer to at least 5 crossword clues on different crossword puzzles. Crossword clues for DESPONDENT Showing 1 to 5 of 5 results Clue(s) Dejected Demoralised person in divorce case losing right to support daughter Downcast or disheartened Downcast, disheartened Lack of hope