Crossword clues for the word: DESPICABLE The word DESPICABLE has appeared as an answer to at least 5 crossword clues on different crossword puzzles. Crossword clues for DESPICABLE Showing 1 to 5 of 5 results Clue(s) Adjective for Bill Sikes Contemptible Contemptible or mean Spied obscene wire; it's contemptible (10) Worthy of keen disapprobation.