Crossword clues for the word: DEFIES The word DEFIES has appeared as an answer to at least 11 crossword clues on different crossword puzzles. Crossword clues for DEFIES Showing 1 to 11 of 11 results Clue(s) Flies in the face of Flouts Goes against Goes up against Openly disobeys Openly opposes Openly resists Resists boldly Stands uo to. Stands up to Throws down the gauntlet