Crossword clues for the word: CANOPUS The word CANOPUS has appeared as an answer to at least 7 crossword clues on different crossword puzzles. Crossword clues for CANOPUS Showing 1 to 7 of 7 results Clue(s) Bright star in Argo. Brightest star after Sirius Brightest star in constellation Carina Major star in Carina Southern star There’s prison work in ancient coastal town Very bright star in Argo